# Domain Analysis Skill Configuration skill: name: domain-analysis version: "1.0.0" description: "蛋白结构域分析 - HMMER+Pfam" author: "bbav2-team" input: protein_fasta: null # 必需: 蛋白序列FASTA文件 pfam_hmm: null # 必需: Pfam HMM模型文件 parameters: hmmscan: evalue: 1e-5 coverage: 0.5 use_cut_ga: false cpu: 8 output: format: ["tsv", "json"] report_template: "templates/report.md.j2" include_reproducibility: true dependencies: conda: channels: - bioconda - conda-forge packages: - hmmer=3.3.2 - biopython=1.81 - pandas=2.0.0 - matplotlib=3.7.0