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PlantAI-dev/scripts/promoter_element_categories.md
2026-08-03 18:42:47 +08:00

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植物顺式作用元件分类规则 (PlantCARE-based)

分类体系

1. 核心启动子元件 (Core Promoter Elements)

  • TATA-box: TATA-box, AT~TATA-box, TATA
  • CAAT-box: CAAT-box, CCAAT-box
  • Inr (Initiator): Inr, Y-patch

2. 光响应元件 (Light Responsive Elements)

  • G-box/G-Box: G-box, G-Box, G-box-like
  • GT1-motif: GT1-motif, GT-1
  • I-box: I-box, I-box core
  • Sp1: Sp1 (light responsive)
  • Box 4: Box 4
  • GATA-motif: GATA-motif

3. 激素响应元件 (Hormone Responsive Elements)

3.1 ABA响应

  • ABRE: ABRE, ABA-responsive element

3.2 赤霉素响应

  • P-box: P-box, GARE (gibberellin-responsive element)
  • Py-box: Py-box

3.3 茉莉酸响应

  • CGTCA-motif: CGTCA-motif
  • TGACG-motif: TGACG-motif

3.4 水杨酸响应

  • TCA-element: TCA-element
  • as-1: as-1

3.5 生长素响应

  • TGA-element: TGA-element
  • AuxRE: AuxRE

3.6 乙烯响应

  • ERE: ERE (ethylene-responsive element)

4. 胁迫响应元件 (Stress Responsive Elements)

4.1 干旱/脱水

  • DRE/CRT: DRE, CRT (C-repeat)
  • MBS: MBS (MYB binding site, drought)

4.2 低温

  • LTR: LTR (low temperature responsive)

4.3 厌氧

  • ARE: ARE (anaerobic responsive element)

4.4 氧化胁迫

  • STRE: STRE (stress responsive element)

4.5 伤口/病原体

  • W box: W box, W-box
  • WRE: WRE3, WRE

5. 转录因子结合位点 (TF Binding Sites)

5.1 MYB家族

  • MYB: MYB, Myb, MYB-like sequence, MYB recognition site
  • MBS: MBS (MYB binding site)
  • MRE: MRE (MYB recognition element)

5.2 MYC/bHLH家族

  • MYC: MYC, MYC recognition site
  • E-box: E-box, CANNTG

5.3 WRKY家族

  • W box: W box (也是WRKY结合位点)

5.4 bZIP家族

  • ABRE: ABRE (也是bZIP结合位点)
  • G-box: G-box (也是bZIP结合位点)

6. 发育调控元件 (Developmental Elements)

6.1 种子特异性

  • RY-element: RY-element, CATGCATG
  • AAGAA-motif: AAGAA-motif

6.2 分生组织

  • CAT-box: CAT-box

6.3 胚乳

  • GCN4-motif: GCN4-motif
  • Skn-1 motif: Skn-1 motif

7. 其他功能元件

  • TCT-motif: TCT-motif
  • Unnamed: Unnamed__1, Unnamed__4, Unnamed__6 等

分类优先级规则

当一个元件可能属于多个类别时,按以下优先级:

  1. 核心启动子元件 (最高优先级)
  2. 激素响应元件
  3. 胁迫响应元件
  4. 转录因子结合位点
  5. 光响应元件
  6. 发育调控元件
  7. 其他 (最低优先级)

参考来源

  1. PlantCARE Database: https://bioinformatics.psb.ugent.be/webtools/plantcare/
  2. Lescot et al. (2002) PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences. Nucleic Acids Res.
  3. New PLACE Database: https://www.dna.affrc.go.jp/PLACE/