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2026-08-03 18:42:47 +08:00

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YAML
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# TFBS Prediction Skill Configuration
skill:
name: tfbs-prediction
version: "1.0.0"
description: "TF binding-site prediction with promoter extraction and MEME Suite FIMO"
author: "bbav5-team"
input:
gff3: null
genome_fasta: null
gene_ids: null
parameters:
upstream_length: 2000
motif_db_mode: auto
fimo_pvalue: 0.0001
fimo_qvalue: 0.05
background_mode: none
max_nearest_rank: order
top_motifs: 30
scan_both_strands: true
cpu: 4
output:
manifest: "{prefix}.tfbs.manifest.json"
tables:
- "{prefix}.tfbs.sites.tsv"
- "{prefix}.tfbs.enrichment.tsv"
- "{prefix}.tfbs.gene_motif_matrix.tsv"
figures:
- "{prefix}.tfbs.*.png"
dependencies:
conda:
channels:
- bioconda
- conda-forge
packages:
- meme
- seqkit
- gffread
- pandas
- scipy
- matplotlib
- seaborn