diff --git a/sdk/app/schemas.py b/sdk/app/schemas.py
index 82ac768..5141ded 100644
--- a/sdk/app/schemas.py
+++ b/sdk/app/schemas.py
@@ -101,9 +101,110 @@ class ArtifactBlock(BaseModel):
     status: str = "done"  # running|done|error（生成中/已就绪/失败）
 
 
+# ---------------------------------------------------------------------------
+# §2b 生信块（BFF 仅做持久化校验，不参与渲染——字段契约归前端 store 与
+# bioflow 服务 SSE 事件；union 判别靠 type 字面量，其余字段全默认值 +
+# extra="allow" 宽松接收，生信功能只部署 rag 时零影响）。
+# ---------------------------------------------------------------------------
+
+class BioflowPathBlock(BaseModel):
+    """生信路径选择卡（FR-BIO-002/003/004）：候选路径列表 + 选中项。"""
+
+    model_config = ConfigDict(extra="allow")
+
+    type: Literal["bioflow_path"] = "bioflow_path"
+    status: str = "running"
+    candidates: list[dict[str, Any]] = Field(default_factory=list)
+    selected: Any = None
+    autoFilled: list[str] = Field(default_factory=list)
+    reuseArchive: Any = None
+    reuseName: Any = None
+    fallback: Any = None
+
+
+class BioflowProgressBlock(BaseModel):
+    """生信阶段进度卡（FR-BIO-013/014）：逐阶段状态流转 + 日志尾。"""
+
+    model_config = ConfigDict(extra="allow")
+
+    type: Literal["bioflow_progress"] = "bioflow_progress"
+    jobId: Any = None
+    jobStatus: str = "created"
+    stages: list[dict[str, Any]] = Field(default_factory=list)
+    autoContinue: bool = False
+
+
+class BioflowFormBlock(BaseModel):
+    """生信参数确认表单卡（FR-BIO-008/012）：阶段参数可编辑表单。"""
+
+    model_config = ConfigDict(extra="allow")
+
+    type: Literal["bioflow_form"] = "bioflow_form"
+    stage: str = ""
+    fields: list[dict[str, Any]] = Field(default_factory=list)
+    autoContinue: bool = False
+    rerun: bool = False
+    submitting: bool = False
+
+
+class BioflowFileBlock(BaseModel):
+    """生信数据文件引导卡（FR-BIO-005/006）：缺失文件提示 + 上传进度。"""
+
+    model_config = ConfigDict(extra="allow")
+
+    type: Literal["bioflow_file"] = "bioflow_file"
+    stage: str = ""
+    requiredFiles: list[str] = Field(default_factory=list)
+    message: str = ""
+    files: list[dict[str, Any]] = Field(default_factory=list)
+
+
+class BioflowArchiveBlock(BaseModel):
+    """生信存档提示卡（FR-BIO-020）：任务完成后提示存档。"""
+
+    model_config = ConfigDict(extra="allow")
+
+    type: Literal["bioflow_archive"] = "bioflow_archive"
+    jobId: Any = None
+    status: str = "pending"  # pending | archiving | done | dismissed | error
+    name: str = ""
+    description: str = ""
+    result: Any = None
+    error: Any = None
+
+
+class BioflowQaBlock(BaseModel):
+    """生信流程知识库咨询引用块（FR-BIO-026）：引用携带 cite 供跳转。"""
+
+    model_config = ConfigDict(extra="allow")
+
+    type: Literal["bioflow_qa"] = "bioflow_qa"
+    question: str = ""
+    citations: list[dict[str, Any]] = Field(default_factory=list)
+    degraded: bool = False
+
+
+class BioflowReuseBlock(BaseModel):
+    """生信存档复用预填表单块（FR-BIO-023）：复用存档方法发起新任务。"""
+
+    model_config = ConfigDict(extra="allow")
+
+    type: Literal["bioflow_reuse"] = "bioflow_reuse"
+    mode: str = "reuse"
+    stage: str = "reuse"
+    archiveId: Any = None
+    archiveName: str = ""
+    sessionId: str = ""
+    target: str = ""
+    fields: list[dict[str, Any]] = Field(default_factory=list)
+    prefill: dict[str, Any] = Field(default_factory=dict)
+
+
 Block = Union[
     TextBlock, TableBlock, CodeBlock, StreamBlock,
     PipelineBlock, ToolBlock, SourcesBlock, GraphBlock, ArtifactBlock,
+    BioflowPathBlock, BioflowProgressBlock, BioflowFormBlock, BioflowFileBlock,
+    BioflowArchiveBlock, BioflowQaBlock, BioflowReuseBlock,
 ]