diff --git a/ui/src/components/chat/FlowPathCard.vue b/ui/src/components/chat/FlowPathCard.vue
index a7192a5..a468758 100644
--- a/ui/src/components/chat/FlowPathCard.vue
+++ b/ui/src/components/chat/FlowPathCard.vue
@@ -62,21 +62,26 @@ function backToSelect() {
 async function confirmCreate() {
   const cand = selectedCandidate.value;
   if (!cand || confirming.value) return;
+  if (props.block.jobId) return; // 已创建过（防重复创建；FR-BIO 任务幂等语义）
   confirming.value = true;
   error.value = '';
   try {
-    const sessionId = chat.sessionId || '';
-    const detail = await bioflow.createJobFromPlan({
-      sessionId,
+    // r4 修复：不再 emit('updated')（该事件全链无人监听，任务创建后 UI 静默）——
+    // 改走 chat store 一站式 confirmBioflowPath：创建 → 挂进度块 → 订阅任务事件
+    // 桥接推进 → 落库。aMsg 从 chat 消息流定位（当前消息 = 含本 path 块的 assistant 消息）。
+    const aMsg = (chat.messages || []).find(
+      (m) => m && m.role === 'assistant' && Array.isArray(m.blocks) && m.blocks.includes(props.block),
+    );
+    const detail = await chat.confirmBioflowPath({
       title: (chat.messages || []).find((m) => m.role === 'user')?.text?.slice(0, 50) || '生信任务',
       stages: cand.stages,
       params: {},
       autoContinue: false,
       archiveId: reuseArchive.value || null,
+      aMsg: aMsg || null,
     });
-    // 进度块由任务事件流/详情回填；此处标记 path 块已确认
-    props.block.jobId = detail.id || null;
-    emit('updated');
+    // 进度块由 confirmBioflowPath 挂载；此处标记 path 块已确认
+    props.block.jobId = (detail && detail.id) || null;
   } catch (err) {
     error.value = err?.message || BF.pathStageCreating;
     emit('flow-error', err);
diff --git a/ui/src/stores/bioflow.js b/ui/src/stores/bioflow.js
index 003db07..25210ba 100644
--- a/ui/src/stores/bioflow.js
+++ b/ui/src/stores/bioflow.js
@@ -273,7 +273,7 @@ export const useBioflowStore = defineStore('bioflow', {
     // 事件订阅（SSE 断线重连回放；EventSource 契约允许测试注入 mock）
     // ---------------------------------------------------------------
     /** 打开 /jobs/{id}/events 订阅（首帧快照整体刷新 + 回放 + 实时；终态服务端关闭） */
-    connectJobEvents(jobId, sessionId, { sourceFactory, onOpen } = {}) {
+    connectJobEvents(jobId, sessionId, { sourceFactory, onOpen, onEvent } = {}) {
       const key = sessionId || 'default';
       this.disconnectJobEvents(key);
       const lastSeq = this.currentJob.lastSeq || 0;
@@ -295,6 +295,10 @@ export const useBioflowStore = defineStore('bioflow', {
           this.applyJobEvent({ type, data, seq });
           if (typeof seq === 'number') rec.lastSeq = Math.max(rec.lastSeq, seq);
         }
+        // 事件桥接（r4 修复：路径卡确认创建后消息进度块与 store 同源推进）
+        if (typeof onEvent === 'function') {
+          try { onEvent(type, data, seq); } catch { /* 桥接异常不阻断事件应用 */ }
+        }
       };
       es.addEventListener('snapshot', (e) => {
         try { apply('snapshot', JSON.parse(e.data || '{}'), 0); } catch { /* 坏帧忽略 */ }
diff --git a/ui/src/stores/chat.js b/ui/src/stores/chat.js
index 489d97c..3926a2d 100644
--- a/ui/src/stores/chat.js
+++ b/ui/src/stores/chat.js
@@ -572,6 +572,32 @@ export const useChatStore = defineStore('chat', {
       this.lastResult = null;
       this.scrollSeq++;
       hydrateBench();
+      // r4 修复：恢复生信任务事件订阅（路径卡确认创建的任务；刷新后进度卡继续流转。
+      // 触发条件：assistant 消息含 bioflow_progress 块且 jobId 非空、任务未终态。
+      // 订阅的 onEvent 桥接把每帧事件 patch 进该消息的进度块（与 confirmBioflowPath 同款）。
+      try {
+        const bioflowStore = useBioflowStore();
+        const BIOFLOW_TERMINAL = new Set(['done', 'paused', 'archived', 'failed', 'error']);
+        for (const m of this.messages) {
+          if (!m || m.role !== 'assistant' || !Array.isArray(m.blocks)) continue;
+          const blk = m.blocks.find((b) => b && b.type === 'bioflow_progress');
+          if (!blk || !blk.jobId || BIOFLOW_TERMINAL.has(blk.jobStatus)) continue;
+          const jobId = blk.jobId;
+          bioflowStore.connectJobEvents(jobId, this.sessionId, {
+            onEvent: (type, data) => {
+              const frame = patchBioflowEvent(m, { type, data });
+              if (frame) this.scrollSeq++;
+              if (type === 'stage_await_confirm' && data) { patchBioflowForm(m, data); this.scrollSeq++; }
+              else if (type === 'stage_await_files' && data) { patchBioflowFile(m, data); this.scrollSeq++; }
+              else if (type === 'job_done' && data) {
+                const ab = patchBioflowArchiveSuggest(m, data.job_id || jobId);
+                if (ab) ab.jobId = data.job_id || jobId;
+                this.scrollSeq++;
+              }
+            },
+          });
+        }
+      } catch { /* 生信未就绪容错 */ }
       // 缺陷 #52：恢复 docgen 任务轮询（hydrate 后 aMsg 已是响应式代理）
       if (this._docgenResumeQueue && this._docgenResumeQueue.length) {
         const queue = this._docgenResumeQueue;
@@ -1360,6 +1386,64 @@ export const useChatStore = defineStore('chat', {
       return null;
     },
 
+    /** 路径卡「确认创建任务」（r4 修复：修复前 FlowPathCard.confirmCreate 自调
+     *  createJobFromPlan 后 emit('updated') 无人监听——任务 201 创建成功但 UI 静默：
+     *  无进度卡、无任务事件订阅、不落库（刷新即丢）。此处把
+     *  「创建 → 挂进度块 → 订阅任务事件（桥接推进消息块）→ 落库」收拢成一站式。
+     *  返回 bioflow store 的 job detail（与 createJobFromPlan 同形，卡片可继续用）。 */
+    async confirmBioflowPath({ title, stages, params, autoContinue, archiveId, aMsg, userMessageId }) {
+      const bioflow = useBioflowStore();
+      const detail = await bioflow.createJobFromPlan({
+        sessionId: this.sessionId || '',
+        title: title || '生信任务',
+        stages,
+        params: params || {},
+        autoContinue: !!autoContinue,
+        archiveId: archiveId || null,
+      });
+      const jobId = (detail && detail.id) || null;
+      if (!jobId || !aMsg) return detail;
+      // 1. 路径卡落定：path 块打 jobId + selected 固化（复用刷新后仍可确认态）
+      const pathBlk = (aMsg.blocks || []).find((b) => b && b.type === 'bioflow_path');
+      if (pathBlk) {
+        pathBlk.jobId = jobId;
+        if (typeof pathBlk.selected !== 'number') pathBlk.selected = 0;
+      }
+      // 2. 进度块：以 job_created 事件形态挂（stage 状态 waiting，jobStatus created）
+      patchBioflowEvent(aMsg, { type: 'job_created', data: { job_id: jobId, auto_continue: !!autoContinue, stages: detail.stages || [] } });
+      // 3. 订阅任务事件并把每帧桥接进消息进度块（与 sendBioflow 流内 openJobEvents 同源）
+      try {
+        bioflow.connectJobEvents(jobId, this.sessionId || '', {
+          onEvent: (type, data, seq) => {
+            const frame = patchBioflowEvent(aMsg, { type, data });
+            if (frame) this.scrollSeq++;
+            if (type === 'stage_await_confirm' && data) {
+              patchBioflowForm(aMsg, data);
+              this.scrollSeq++;
+            } else if (type === 'stage_await_files' && data) {
+              patchBioflowFile(aMsg, data);
+              this.scrollSeq++;
+            } else if (type === 'job_done' && data) {
+              const blk = patchBioflowArchiveSuggest(aMsg, data.job_id || jobId);
+              if (blk) blk.jobId = data.job_id || jobId;
+              bioflow.registerReport({
+                jobId: data.job_id || jobId,
+                sessionId: this.sessionId || '',
+                title: bioflow.currentJob.title || '生信分析报告',
+                reportPath: data.report_path || '',
+                figures: Array.isArray(data.figures) ? data.figures : [],
+              }).catch(() => {});
+              this.scrollSeq++;
+            }
+          },
+        });
+      } catch { /* EventSource 不可用：任务事件仍由快照兜底 */ }
+      // 4. 落库（刷新后进度卡不丢；jobId 随块持久化）
+      await this._persistFinal(aMsg, this.sessionId, 'streaming', { raw: aMsg.raw }).catch(() => {});
+      this.scrollSeq++;
+      return detail;
+    },
+
     /** 上传文件到生信任务（XHR 进度；FR-BIO-006）。返回登记结果。 */
     async uploadBioflowFileToJob(jobId, file, { onProgress } = {}) {
       const { uploadBioflowFile } = await import('../api/bioflow.js');
diff --git a/ui/tests/r3debug/bioflowPathConfirm.test.js b/ui/tests/r3debug/bioflowPathConfirm.test.js
new file mode 100644
index 0000000..22faa29
--- /dev/null
+++ b/ui/tests/r3debug/bioflowPathConfirm.test.js
@@ -0,0 +1,191 @@
+// tests/r3debug/bioflowPathConfirm.test.js —— 生信路径卡确认创建后 UI 断链修复
+// 缺陷:FlowPathCard.confirmCreate 创建任务成功后 emit('updated') 无人监听,
+//   UI 无进度卡/无事件订阅/不落库(刷新即丢)。修复后走 store 一站式 confirmBioflowPath。
+import { describe, it, expect, vi, beforeEach, afterEach } from 'vitest';
+import { setActivePinia, createPinia } from 'pinia';
+
+vi.mock('../../src/api/sessions.js', () => ({
+  createMessage: vi.fn(async () => ({ id: 'm' + Math.random().toString(36).slice(2, 6) })),
+  updateMessage: vi.fn(async () => ({ updated_at: new Date().toISOString() })),
+}));
+vi.mock('../../src/api/qa.js', () => ({
+  chatStream: vi.fn(async () => {}),
+  search: vi.fn(async () => ({ answer: '' })),
+}));
+vi.mock('../../src/api/private.js', () => ({
+  askPrivate: vi.fn(async () => ({ hit: false })),
+}));
+vi.mock('../../src/api/docgen.js', () => ({
+  generate: vi.fn(), getTask: vi.fn(),
+  getArtifactContent: vi.fn(async () => ({ markdown: '' })),
+  getArtifactHtml: vi.fn(async () => ({ ok: true, html: '', css: '' })),
+  saveArtifactContent: vi.fn(async () => ({})), editArtifact: vi.fn(async () => ({})),
+  exportArtifact: vi.fn(async () => ({})), uploadLibrary: vi.fn(),
+  listLibrary: vi.fn(async () => ({ items: [] })), removeLibrary: vi.fn(async () => ({ ok: true })),
+  listTasks: vi.fn(async () => ({ tasks: [] })),
+}));
+
+const connectJobEventsSpy = vi.fn();
+const createJobFromPlanSpy = vi.fn();
+vi.mock('../../src/stores/bioflow.js', async () => {
+  const actual = await vi.importActual('../../src/stores/bioflow.js');
+  const { useBioflowStore: useReal } = actual;
+  return {
+    ...actual,
+    useBioflowStore: () => {
+      const st = useReal();
+      st.connectJobEvents = connectJobEventsSpy;
+      st.createJobFromPlan = createJobFromPlanSpy;
+      return st;
+    },
+  };
+});
+
+import { useChatStore } from '../../src/stores/chat.js';
+import { useSessionsStore } from '../../src/stores/sessions.js';
+import { useBioflowStore } from '../../src/stores/bioflow.js';
+import { updateMessage } from '../../src/api/sessions.js';
+
+function freshStores() {
+  const pinia = createPinia();
+  setActivePinia(pinia);
+  const chat = useChatStore();
+  const sessions = useSessionsStore();
+  chat.sessionId = 's1';
+  sessions.activeId = 's1';
+  sessions.items = [{ id: 's1', title: 't', status: 'done', created_at: '', updated_at: '' }];
+  return { chat, sessions };
+}
+
+describe('confirmBioflowPath 一站式任务创建', () => {
+  beforeEach(() => {
+    connectJobEventsSpy.mockReset();
+    createJobFromPlanSpy.mockReset();
+    vi.mocked(updateMessage).mockClear();
+  });
+
+  it('创建成功 → 挂 job_created 进度块 + 订阅任务事件 + 落库', async () => {
+    const { chat } = freshStores();
+    createJobFromPlanSpy.mockResolvedValue({
+      id: 'job-1', title: '生信任务', status: 'created',
+      stages: [
+        { stage: 'genome_prepare', status: 'waiting' },
+        { stage: 'identify', status: 'waiting' },
+      ],
+    });
+    const aMsg = {
+      id: 'am1', role: 'assistant', status: 'done',
+      blocks: [
+        { type: 'bioflow_path', status: 'done', candidates: [{ stages: ['genome_prepare', 'identify'] }], selected: 0 },
+      ],
+      raw: {},
+    };
+    chat.messages = [aMsg];
+
+    const detail = await chat.confirmBioflowPath({
+      title: '生信任务',
+      stages: ['genome_prepare', 'identify'],
+      aMsg,
+    });
+
+    // 1. 返回 detail 与创建入参一致
+    expect(detail.id).toBe('job-1');
+    // 2. path 块落定 jobId + selected 固化
+    const pathBlk = aMsg.blocks.find((b) => b.type === 'bioflow_path');
+    expect(pathBlk.jobId).toBe('job-1');
+    expect(pathBlk.selected).toBe(0);
+    // 3. 进度块挂上且 jobStatus=created、阶段 waiting
+    const progBlk = aMsg.blocks.find((b) => b.type === 'bioflow_progress');
+    expect(progBlk).toBeTruthy();
+    expect(progBlk.jobId).toBe('job-1');
+    expect(progBlk.jobStatus).toBe('created');
+    expect(progBlk.stages.length).toBe(2);
+    // 4. 订阅了任务事件流(带 onEvent 桥接)
+    expect(connectJobEventsSpy).toHaveBeenCalledTimes(1);
+    expect(connectJobEventsSpy.mock.calls[0][0]).toBe('job-1');
+    expect(typeof connectJobEventsSpy.mock.calls[0][2].onEvent).toBe('function');
+    // 5. 落库(updateMessage 调用)
+    expect(updateMessage).toHaveBeenCalled();
+  });
+
+  it('onEvent 桥接把任务事件 patch 进消息进度块(阶段推进)', async () => {
+    const { chat } = freshStores();
+    createJobFromPlanSpy.mockResolvedValue({
+      id: 'job-2', title: '生信任务', status: 'created', stages: [{ stage: 'identify', status: 'waiting' }],
+    });
+    const aMsg = {
+      id: 'am2', role: 'assistant', status: 'done',
+      blocks: [{ type: 'bioflow_path', candidates: [{ stages: ['identify'] }], selected: 0 }],
+      raw: {},
+    };
+    chat.messages = [aMsg];
+    await chat.confirmBioflowPath({ title: 't', stages: ['identify'], aMsg });
+
+    const onEvent = connectJobEventsSpy.mock.calls[0][2].onEvent;
+    onEvent('stage_started', { job_id: 'job-2', stage: 'identify' });
+    onEvent('stage_done', { job_id: 'job-2', stage: 'identify' });
+
+    const progBlk = aMsg.blocks.find((b) => b.type === 'bioflow_progress');
+    const st = progBlk.stages.find((s) => s.stage === 'identify');
+    expect(st.status).toBe('done'); // 终态不回退语义保持
+  });
+
+  it('job_done 事件 → 挂存档提示块', async () => {
+    const { chat } = freshStores();
+    createJobFromPlanSpy.mockResolvedValue({
+      id: 'job-3', title: '生信任务', status: 'created', stages: [{ stage: 'identify', status: 'waiting' }],
+    });
+    const aMsg = {
+      id: 'am3', role: 'assistant', status: 'done',
+      blocks: [{ type: 'bioflow_path', candidates: [{ stages: ['identify'] }], selected: 0 }],
+      raw: {},
+    };
+    chat.messages = [aMsg];
+    await chat.confirmBioflowPath({ title: 't', stages: ['identify'], aMsg });
+
+    connectJobEventsSpy.mock.calls[0][2].onEvent('job_done', { job_id: 'job-3', report_path: '/r.html', figures: [] });
+
+    const archBlk = aMsg.blocks.find((b) => b.type === 'bioflow_archive');
+    expect(archBlk).toBeTruthy();
+    expect(archBlk.jobId).toBe('job-3');
+  });
+
+  it('创建失败不挂块、不落库', async () => {
+    const { chat } = freshStores();
+    createJobFromPlanSpy.mockRejectedValue(new Error('创建失败'));
+    const aMsg = {
+      id: 'am4', role: 'assistant', status: 'done',
+      blocks: [{ type: 'bioflow_path', candidates: [{ stages: ['identify'] }], selected: 0 }],
+      raw: {},
+    };
+    chat.messages = [aMsg];
+    await expect(
+      chat.confirmBioflowPath({ title: 't', stages: ['identify'], aMsg }),
+    ).rejects.toThrow('创建失败');
+    expect(aMsg.blocks.some((b) => b.type === 'bioflow_progress')).toBe(false);
+    expect(updateMessage).not.toHaveBeenCalled();
+  });
+
+  it('hydrateDetail 恢复订阅:含未终态进度块的消息重连事件流', async () => {
+    const { chat, sessions } = freshStores();
+    const progressBlk = { type: 'bioflow_progress', jobId: 'job-9', jobStatus: 'running', stages: [] };
+    sessions.fetchDetail = vi.fn(async () => ({
+      messages: [
+        { id: 'u1', role: 'user', text: 'q' },
+        { id: 'a1', role: 'assistant', kind: 'qa', status: 'done', blocks: [progressBlk], raw: {} },
+      ],
+    }));
+    await chat.loadSession('s1');
+
+    expect(connectJobEventsSpy).toHaveBeenCalledWith('job-9', 's1', expect.anything());
+    // 终态不重连
+    connectJobEventsSpy.mockClear();
+    sessions.fetchDetail = vi.fn(async () => ({
+      messages: [
+        { id: 'a2', role: 'assistant', kind: 'qa', status: 'done', blocks: [{ type: 'bioflow_progress', jobId: 'job-10', jobStatus: 'done', stages: [] }], raw: {} },
+      ],
+    }));
+    await chat.loadSession('s1');
+    expect(connectJobEventsSpy).not.toHaveBeenCalled();
+  });
+});